Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil
1,000 mg (1 g)
***
Cis-Linoleic Acid (LA)
730 mg
***
Gamma-Linolenic Acid (GLA)
90 mg
***
Top Medical Research Studies
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
Read More
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Read More
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
Read More
Most Useful Reviews
8
Minimises blood clots
18 people found this helpful
Evening primrose oil can aid in alleviating conditions related to PMS and menopause, as well as skin issues like eczema and acne. It helps prevent tumour formation, boosts immunity, enhances blood composition, lowers cholesterol, and reduces the risk of blood clots. Furthermore, it normalises blood pressure and regulates blood sugar levels, whilst positively impacting the skin, hair, and nails. Regular use of this oil demonstrates antimicrobial, regenerative, and anti-inflammatory properties.
Read More
7.5
Balances hormones
Evening primrose oil significantly diminishes PMS symptoms, balances hormonal levels, and promotes pregnancy during planning. It normalises blood pressure and positively influences a woman’s well-being in the premenstrual phase and menopause. I purchased this for a friend recovering from surgery; I hope it assists her. Thank you for the thumbs up!
Read More
6
Improves blood flow
This oil helps enhance blood flow during menstruation.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
- All Researches
9
We explored how evening primrose oil might affect blood clotting in rabbits fed a high-cholesterol diet. Using a group of 40 rabbits, we supplemented their diet for 6 weeks with evening primrose oil.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
The results showed promising anti-thrombotic effects. Evening primrose oil reduced cholesterol levels and improved good HDL cholesterol. Additionally, it lessened platelet adhesion to the endothelium and decreased signs of vascular damage.
Overall, we found that this dietary supplement can enhance endothelial health and may help reduce clot formation.
Read More
8
Evening primrose oil reduces clotting risk
We investigated how evening primrose oil (EPO) influences blood clotting when paired with celecoxib, a medication linked to thrombotic events. Using a mouse model, we administered celecoxib alongside EPO or forskolin for four weeks, followed by a prothrombotic challenge.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Our findings suggest that while celecoxib increased thrombotic markers, the addition of EPO significantly reduced this prothrombotic effect. This indicates that EPO may help offset some negative cardiovascular impacts of celecoxib, proving its potential in clinical use.
Read More
8
We investigated how evening primrose oil (EPO) affects blood clotting and blood pressure fluctuations caused by celecoxib in rats. Our study showed that celecoxib raised blood pressure and sped up blood clotting by increasing platelet activity. While EPO helped lower blood pressure and reduced platelet aggregation, omega-3 fatty acids did not have the same effect. This suggests EPO could be a helpful supplement to mitigate cardiovascular risks linked to celecoxib treatment.
Read More
8
We examined the effects of evening primrose oil (EPO) on blood platelet aggregation, a key factor in blood clot formation. Over six weeks, 40 male rabbits were divided into groups and fed either a normal diet or an atherogenic diet, with some receiving EPO.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
The atherogenic diet increased platelet aggregation significantly. However, EPO supplementation notably reduced this hyperaggregation to normal levels. Additionally, it helped lower thromboxane levels and lipid peroxides, which are markers linked to clotting issues.
Overall, these findings suggest that EPO may offer protective benefits against excessive blood clotting in diets high in unhealthy fats.
Read More
7
Evening primrose oil shows limited effectiveness
We explored the impact of evening primrose oil (EPO) on patients with Raynaud's phenomenon (RP) by conducting a double-blind study. Initially, 21 participants received a two-week placebo course. Following this, 11 patients were given EPO for eight weeks while 10 continued with placebo. Overall, those on EPO reported fewer attacks during colder weather and reported improvements in symptoms.
However, objective measures like hand temperatures and blood flow tests didn't show significant improvement. While there were some observed antiplatelet effects and changes in platelet behavior, the treatment did not lead to marked changes in blood clotting relevant to blood flow improvement.
However, objective measures like hand temperatures and blood flow tests didn't show significant improvement. While there were some observed antiplatelet effects and changes in platelet behavior, the treatment did not lead to marked changes in blood clotting relevant to blood flow improvement.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
8
Minimises blood clots
18 people found this helpful
Evening primrose oil can aid in alleviating conditions related to PMS and menopause, as well as skin issues like eczema and acne. It helps prevent tumour formation, boosts immunity, enhances blood composition, lowers cholesterol, and reduces the risk of blood clots. Furthermore, it normalises blood pressure and regulates blood sugar levels, whilst positively impacting the skin, hair, and nails. Regular use of this oil demonstrates antimicrobial, regenerative, and anti-inflammatory properties.
Read More
7.5
Balances hormones
Evening primrose oil significantly diminishes PMS symptoms, balances hormonal levels, and promotes pregnancy during planning. It normalises blood pressure and positively influences a woman’s well-being in the premenstrual phase and menopause. I purchased this for a friend recovering from surgery; I hope it assists her. Thank you for the thumbs up!
Read More
6
Improves blood flow
This oil helps enhance blood flow during menstruation.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Mosaad SM, Zaitone SA, Ahmed AA, Abo-Elmatty DM, El-Baz AA, et al. Evening primrose oil or forskolin ameliorates celecoxib-enhanced upregulation of tissue factor expression in mice subjected to lipopolysaccharide-induced endotoxemia. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:483. doi:10.1007/s00210-017-1342-y
- Zaitone SA, Moustafa YM, Mosaad SM, El-Orabi NF. Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. J Cardiovasc Pharmacol. 2011;58:72. doi:10.1097/FJC.0b013e31821c8353
- Villalobos MA, De La Cruz JP, Martín-Romero M, Carmona JA, Smith-Agreda JM, et al. Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits. Thromb Haemost. 1998;80:696.
- De La Cruz JP, Martín-Romero M, Carmona JA, Villalobos MA, Sánchez de la Cuesta F. Effect of evening primrose oil on platelet aggregation in rabbits fed an atherogenic diet. Thromb Res. 1997;87:141.
- Belch JJ, Shaw B, O'Dowd A, Saniabadi A, Leiberman P, et al. Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study. Thromb Haemost. 1985;54:490.
